Revistas Internacionales

2011 Cáceres M, Romero A, Copaja M, Díaz-Araya G, Martínez J, Smith PC. Simvastatin alters fibroblastic cell responses involved in tissue repair. J Periodontal Res 2011; 46(4):456-463

2011 Cáceres M, Martínez C, Martínez J, Smith PC. Effects of platelet-rich and -poor plasma on the reparative response of gingival fibroblasts. Clin Oral Implants Res 2011 Sep 8 (In Press)

2010 Guerrero J, Tobar N, Cáceres M, Espinoza L, Escobar P, Dotor J, Smith PC, Martinez J. Soluble factors derived from tumor mammary cell lines induce a stromal mammary adipose reversion in human and mice adipose cells. Possible role of TGF-β1 and TNF-a. Breast Cancer Res Treat 2010; 119(2): 497-508

2010 Oyarzún AD, Arancibia R, Hidalgo R, Peñafiel C, Cáceres M, Gonzales M-J, Martinez J, Smith PC. Involvement of MT1-MMP and TIMP-2 in human periodontal disease. Oral Dis 2010; 16(4):388-395

2010 Tobar N, Guerrero J, Smith PC, Martinez J. NOX4-dependent ROS production by stromal mammary cells modulates epithelial MCF-7 cell migration. Br J Cancer 2010; 103(7):1040-1047

2010 Cifuentes M, Mattar P, Fuentes C, Tobar N, Hugo E, Ben-Jonathan N, Rojas C, Martinez J. Obesity-associated proinflammatory cytokines increase calcium sensing receptor (CaSR) protein expression in primary human adipocytes and LS14 human adipose cell line. Arch Biochem Biophys 2010; 500(2):151-156

2009 Smith PC, Guerrero J, Tobar N, Cáceres M, Gonzáles MJ, Martinez J. TNF-alpha stimulated MT1-MMP production is modulated by epidermal growth factor receptor signaling in human gingival fibroblasts. J Periodontal Res 2009; 44:73-80

2009 Arancibia R, Cáceres M, Martínez J, Smith PC. Triclosan inhibits tumor necrosis factor-alpha-stimulated urokinase production in human gingival fibroblasts. J Periodontal Res 2009; 44(6):726-735

2008 Cáceres M, Tobar N, Guerrero J, Smith PC, Martinez J.
c-jun-NH2JNK mediates invasive potential and EGFR activation by regulating the expression of HB-EGF in a urokinase-stimulated pathway.
J Cell Biochem 2008; 103:986-993

2008 Tobar N, Cáceres M, Santibáñez JF, Smith PC, Martinez J.
Rac1 activity and intracellular ROS modulate the migratory potential of MCF-7 cells through a NADPH oxidase and NFkappaB-dependent mechanism.
Cancer Lett 2008; 267: 125–132

2008 Cáceres M, Hidalgo R, Sanz A, Riera P, Martinez J, Smith PC.
Effect of platelet-rich plasma on cell adhesion, cell migration and myofibroblastic differentiation in human gingival fibroblasts.
J Periodontol 2008; 79:714-720

2008 Santos JL, Amador P, Valladares M, Albala C, Martínez JA, Marti A.
Obesity and eating behaviour in a three-generation Chilean family with carriers of the Thrl50Ile mutation in the melanocortin-4 receptor gene.
J Physiol Biochem 2008; 64(3):205-210

2008 Tobar N, Cáceres M, Santibañez JF, Smith PC, Martínez J.
RAC1 activity and intracellular ROS modulate the migratory potential of MCF-7 cells through a NADPH oxidase and NFkappaB-dependent mechanism.
Cancer Lett 2008; 267(1):125-132

2006 Cárcamo C, Pardo E, Oyanedel C, Bravo-Zehnder M, Bull P, Cáceres M, Martinez J, Massardo L, Jacobelli S, González A, Soza A. Galectin-8 binds specific beta1 integrins and induces polarized spreading highlighted by asymmetric lamellipodia in Jurkat T cells.
Exp Cell Res 2006; 312(4):374-386

2006 Smith PC, Martinez J.
Differential uPA expression by TGF-beta1 in gingival fibroblasts.
J Dent Res 2006; 85(2):150-155

2006 Smith PC, Cáceres M, Martinez J.
Induction of the myofibroblastic phenotype in human gingival fibroblasts by transforming growth factor-beta1: role of RhoA-ROCK and c-Jun N-terminal kinase signaling pathways.
J Periodontal Res 2006; 41(5):418-425

2005 Caceres M, Guerrero J, Martinez J.
Overexpression of RhoA-GTP induces activation of the Epidermal Growth Factor Receptor, dephosphorylation of focal adhesion kinase and increased motility in breast cancer cells.
Exp Cell Res 2005; 309(1):229-238

2005 Moreno-Aliaga MJ, Santos JL, Marti A, Martínez JA Does weight loss prognosis depend on genetic make-up? Obes Rev 2005; 6(2):155-168

2004 Guerrero J, Santibañez JF, Gonzalez A, Martinez J.
EGF receptor transactivation by urokinase receptor stimulus through a mechanism involving Src and matrix metalloproteinases.
Exp Cell Res 2004; 292(1):201-208

2004 Martí A, Moreno-Aliaga MJ, Ochoa MC, Marrades P, Santos JL, Martínez JA. Genética de la obesidad en humanos: rumbos de investigación. Rev Esp Obes 2004; 2:351-362

2004 Smith PC, Santibañez JF, Morales JP, Martinez J.
Epidermal growth factor stimulates urokinase-type plasminogen activator expression in human gingival fibroblasts. Possible modulation by genistein and curcumin.
J Periodontal Res 2004; 39(6):380-387

2003 Rojas C, Martínez J, Flores I, Hoffman DR, Uauy R.
Gene expression analysis in human fetal retinal explants treated with docosahexaenoic acid.
Invest Ophthalmol Vis Sci 2003; 44(7):3170-3177

2003 Santibañez JF, Olivares D, Guerrero J, Martinez J.
Cyclic AMP inhibits TGFbeta 1-induced cell-scattering and invasiveness in murine-transformed keratinocytes.
Int J Cancer 2003; 107(5):715-720

2002 Rojas C, Greiner RS, Fuenzalida LC, Martínez J, Salem N Jr, Uauy R.
Long-term n-3 FA deficiency modifies peroxisome proliferator-activated receptor beta mRNA abundance in rat ocular tissues.
Lipids 2002; 37(4):367-374

2002 Santos JL, Perez Bravo F, Martínez JA, Montalvo D, Albala C, Carrasco E.
No evidence for an association between genetic polymorphisms of beta(2)-and beta(3)-adrenergic receptor genes with body mass index in Aymara natives from Chile.
Nutrition 2002; 18(3):255-258

2002 Santibañez JF, Guerrero J, Quintanilla M, Fabra A, Martinez J.
Transforming growth factor-beta 1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytes.
Biochem Biophys Res Commun 2002; 296(2):267-273

2002 Santibañez JF, Quintanilla M, Martinez J.
TGF-beta(1) and Smad4 overexpression induce a less invasive phenotype in highly invasive spindle carcinoma cells.
Febs Lett 2002; 520(1-3):171-176

2001 Juretic N, Santibañez JF, Hurtado C, Martinez J.
ERK 1,2 and p38 pathways are involved in the proliferative stimuli mediated by urokinase in osteoblastic SaOS-2 cell line.
J Cell Biochem 2001; 83:92-98

2000 Rodriguez JP, Montecinos L, Rios S, Reyes P, Martinez J.
Mesenchymal stem cells from osteoporotic patients produce a type I collagen-deficient extracellular matrix favoring the adipogenic differentiation.
J Cell Biochem 2000; 79:557-565

2000 Santibañez JF, Iglesias M, Frontelo P,, Martinez J, Quintanilla M.
Involvement of the Ras/MAPK signaling pathway in the modulation of urokinase production and cellular invasiveness by transforming growth factor-b1 in transformed keratinocytes.
Biochem Biophys Res Commun 2000; 273:521-527

2000 Santibañez JF, Quintanilla M, Martinez J.
Genistein and curcumin block TGF-b1 induced uPA expression and migratory and invasive phenotype in mouse epidermal keratinocytes.
Nutr Cancer 2000; 37(1):49-54

1999 Martinez J, Fuentes M, Cambiazo V, Santibañez JF.
Bone extracellular matrix stimulates invasiveness of estrogen-responsive human mammary MCF-7 cell line.
Int J Cancer 1999; 83:278-282

1999 Santibañez JF, Frontelo P, Iglesias M, Martinez J, Quintanilla M.
Urokinase expression and binding activity associated with the transforming growth factor b1-induced migratory and invasive phenotype of mouse epidermal keratinocytes.
J Cell Biochem 1999; 74:61-73

1998 Depix MS, Martinez J, Santibañez JF, Rovirosa J, San Martin AS, Maccioni R B.
The compound 14 keto-stypodiol diacetato from the algae Stypopodium flabelliforme inhibits microtubules and cell proliferation in DU-145 human prostatic cells.
Mol Cell Biochem 1998; 187:191-199

1998 Rodriguez JP, Santibañez JF, Martinez J.
Soluble factors secreted by PC-3 cells induce structural changes in proteoglycans produced by fetal rat osteoblasts.
Tumour Biol 1998; 19:19-29

1997 Santibañez JF, Navarro A, Martinez J.
Genistein inhibits proliferation and in vitro invasive potential of human tumoral prostatic cell lines.
Anticancer Res 1997; 17:1199-1204

1996 Santibañez JF, Silva S, Martinez J.
Soluble factors produced by PC-3 prostate cells decrease collagen content and mineralization rate in fetal rat osteoblasts in culture.
Br J Cancer 1996; 74:418-422

1996 Martinez J, Silva S, Santibañez JF.
Prostate-derived soluble factors block osteoblast differentiation in culture.
J Cell Biochem 1996; 61(1):18-25

1995 Santibañez JF, Maccioni RB, Martinez J.
Antimicrotubule drugs inhibits secretion of tumoral proteinases in bladder carcinoma cells.
Cell Biochem Function 1995; 13:217-225

1994 Martinez J, Santibañez JF.
Surface associated plasminogen activation in leukemic cells : interaction with extra cellular matrix.
Eur J Cell Biol 1994; 64:257-263

1993 Santibañez JF, Martinez J.
Membrane-associated procollagenase of leukemic cells is activated by urokinase-type plasminogen activator.
Leuk Res 1993; 17:1057-1062

1993 Martinez J, Santibañez JF.
Extracellular calcium modulates proliferation of factor dependent hemopoietic cells.
Cell Biochem Funct 1993; 11:101-105

1992 Martinez J, Santibañez JF, Vial C, Maccioni R.
The anti-neoplasic agent estramustine inhibits secretion of interleukin 3 in leukemic cells. Posible role of MAPs.
Mol Cell Biochem 1992; 117:165-173

1990 Fernandez M, Martinez J, Minguell J.
Collagenase-like activity associated to the leukemic WEHI-3B cell line.
Leuk Res 1990; 14(7):661-666

1989 Fernandez M, Barahona C, Martinez J, Minguell J.
Changes in collagen synthesis by human bone marrow fibroblasts with progressive subcultivation.
Exp Cell Biol 1989; 57:257-263

1987 Martinez J, Minguell J.
Triglyceride synthesis by human bone marrow fibroblasts.
Exp Hematol 1987; 15:221-225

1982 Carvajal N, Acoria M, Rodriguez JP, Fernandez M, Martinez J.
Evidence for cooperative effects in human liver arginase.
Biochim Biophys Acta 1982; 701:146-148

1982 Carvajal N, Fernandez M, Rodriguez JP, Martinez J.
Negative cooperativity in human liver argininosuccinase.
Biochim Biophys Acta 1982; 701:408-409

1978 Carvajal N, Martinez J, Montes de Oca F, Rodriguez JP, Fernandez M.
Subunit interactions and immobilised dimers of human liver arginase.
Biochim Biophys Acta 1978; 527:1-7

1977 Carvajal N, Martinez J, Fernandez M.
Inmobilised monomers of human liver arginase.
Biochim Biophys Acta 1977; 481:177-183

Revistas Nacionales

2006 Santos JL, Patiño A, Aangel B, Martínez JA, Perez Bravo F, Villarroel AC, Sierrasesúmaga L, Albala C.
Asociación entre polimorfismos de la región promotora del gen del factor de necrosis tumoral alfa (TNF-alfa) con obesidad y diabetes en mujeres chilenas (TNF-alfa)con obesidad y diabetes en mujeres chilenas (Association between tumor necrosis factor-alpha promoter polymorphisms and type 2 diabetes and obesity in Chilean elderly women).
Rev Med Chil 2006; 134:1099-1106

2005 Santos JL, Martínez JA, Perez Bravo F, Albala C.
Epidemiología genética de la obesidad: estudios familiares (Genetic epidemiology of obesity. Family studies).
Rev Med Chil 2005;133(3):349-361

2000 Uauy R, Martinez J, Rojas C.
Bases moleculares de la regulación del metabolismo de lípidos: papel del sistema PPAR (Molecular nutrition, role of the PPAR system in lipidic metabolism and its importance in obesity and diabetes mellitus).
Rev Med Chil 2000; 128:437-446

1996 Rosselot G, Martinez J, Rodriguez JP.
Bases celulares del desarrollo del tejido óseo (Cellular basis of bone tissue development).
Rev Med Chil 1996; 124(8 Supl):15-20

1996 Martinez J, Rosselot G, Rodriguez JP.
Aspectos moleculares del fenómeno osteogénico (Molecular aspects of osteogenic phenomena).
Rev Med Chil 1996; 124(8 Supl):21-28

1995 Hidalgo C, Martinez J.
La investigación científica en la Universidad de Chile: una mirada contingente (Scientific investigation in the University of Chile. A contingent sight).
Anales de la Universidad de Chile 1995; 6º serie (2):25-38

1988 Minguell J, Fernandez M, Tetas M, Martinez J, Bruzzone M, Rodriguez JP.
Microambiente hematopoyético : elementos celulares y de matriz extracelular (Bone marrow microenvironment).
Arch Biol Med Exp 1988; 21:177-182

Publicaciones

Libros

2008 Martínez R, Fernández A, Espíndola E, Flores L, Montoya AM, Oviedo E, Peroni A, Vio F, Martinez J, Mendez M, Ivanovic D. The cost of hunger: Social and economic impact of child undernutrition in Central America and the Dominican Republic. Summary Report. Santiago: United Nations, World Food programme (PMA)-Economic Commission for Latin America and the Caribbean (ECLAC); 2008

2007 Martinez R, Fernández A, Espíndola E, Flores L, Montoya AM, Oviedo E, Peroni A, Vio F, Martinez J, Mendez M, Ivanovic D. El costo del hambre. Análisis del impacto social y económico de la desnutrición infantil en América Latina. Resultados del estudio en Centroamérica y República Dominicana. Panorama general (The cost of hunger. Social and economic impact of child undernutrition in Latin America. Results of Central America and the Domican Republic study. General panorama). Santiago: Naciones Unidas, Programa Mundial de Alimentos (PMA)-Comisión Económica para América Latina (CEPAL), División de Desarrollo Social; 2007

2006 Martínez R, Fernández A., editores.
Colaboradores: Oviedo E, Espínola E, Flores L, Montoya AM, Peroni A, Vio F, Martinez J, Mendez M, Ivanovic D.
Modelo de análisis del impacto social y económico de la desnutrición infantil en América Latina (Model of analysis of the social and economic impact of input undernutrition in Latin America).
Santiago: CEPAL, Naciones Unidas, División de Desarrollo Social; 2006 (Serie Manuales; 52).

Capítulos de Libros

Informes Internacionales

Informes Nacionales

Monografías

1995 Vio F, Albala C, Garcia F, Martinez J, Uauy R.
Consecuencias de la transición epidemiológica en la salud y nutrición del adulto en Chile.
Santiago: INTA; 1995 (Monografía INTA/95/1)

Programas Informáticos