Revistas Internacionales

2011 Valenzuela A, Delplanque B, Tavella M. Stearic acid: a possible substitute for trans fatty acids from industrial origin. Grasas & Aceites 2011; 62:131-138

2010 Valenzuela A, Nieto S, Sanhueza J, Morgado N, Rojas I, Zañartu P. Supplementing female rats with DHA-lysophosphatidylcholine increases docosahexaenoic acid and acetylcholine contents in the brain and improves the memory and learning capabilities of the pups. Grasas & Aceites 2010; 61:16-23

2010 Valenzuela A. Acidos grasos y enfermedades del aparato circulatorio (Fatty acids and circulatory system diseases). Aceites & Grasas 2010; 20:290-297

2009 Haim D, Berríos M, Valenzuela A, Videla LA. Trace quantification of 1-octacosanol and 1-triacontanol and their main metabolites in plasma by liquid–liquid extraction coupled with gas chromatography–mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2009; 877(32):4154-4158

2009 Valenzuela A.
El ácido docosahexaenoic (DHA), un ácido graso esencial para la adecuada función de las células neuronales: Su efecto en los desórdenes del comportamiento (Docosahexaenoic acid (DHA), an essential fatty acid for the proper functioning of neuronal cells: Their role in mood disorders).
Grasas & Aceites 2009; 60(2):203-212

2009 Valenzuela A, Sanhueza, J. El tejido adiposo: Algo más que un reservorio de energía (The adipose tissue: Something more than a reservoir of energy). Grasas & Aceites 2009; 60: 437-452

2009 Valenzuela A. Aceites de origen marino y su importancia en la salud y nutrición humana y animal (Marine origin oils and their importance in human and animal nutrition and health). Aceites y Grasas 2009; 19:154-161

2008 Valenzuela A, Del Planque B, Tavella M. El ácido esteárico, un posible sustituto nutricional de los ácidos grasos trans (Stearic acid, a possible nutritional substitute for trans fatty acids). Aceites & Grasas 2008; 18(71):71-79

2008 Valenzuela A, Sanhueza J. Lípidos estructurados y los sustitutos de grasas, los lípidos del futuro (Structured lipids and fat substitutes, the lipids of the future). Aceites & Grasas 2008; 18(72):230-237

2007 Sanhuieza J, Valenzuela A.
Acido linoleico conjugado (CLA), un isómero trans con potenciales efectos beneficiosos para la salud (Conjugated linoleic acid (CLA), a trans isomer with potential beneficial health effects).
Aceites& Grasas 2007; 17: 244-256

2007 Valenzuela A.
El chocolate y su importancia (Chocolate And its importante.
Aceites & Grasas 2007; 17: 168-175

2007 Valenzuela A, Morgado N.
Ácidos grasos trans: Su origen, impacto sobre la salud y alternativas para su reducción en alimentos (Trans fatty acids: Sources, health impact and its possible reduction in foods).
Aceites & Grasas 2007; 17:586-599

2006 Valenzuela A, Ronco AM.
Los fitoesteroles: Lípidos de origen natural que protegen la salud (Phytosterols: natural lipids that protect health).
Aceites & Grasas 2006; 14(4):560-567

2006 Valenzuela A, Sanhueza J, Nieto S.
Docosahexaenoic acid (DHA), essentiality and requirements: why and how to provide supplementation.
Grasas & Aceites 2006; 57(2):229-237

2006 Valenzuela A.
La historia del colesterol y su relación con las enfermedades cardiovasculares (The history of cholesterol and its relation with cardiovascular diseases).
Aceites & Grasas 2006; 14(1):152-155

2005 Valenzuela A, Nieto S, Sanhueza J, Nuñez MJ, Ferrer C.
Tissue accretion and milk content of docosahexaenoic acid in female rats after supplementation with different docosahexaenoic acid sources.
Ann Nutr Metab 2005; 49(5):325-332

2005 Valenzuela A, Valenzuela V, Sanhueza J, Nieto S.
Effect of supplementation with docosahexaenoic acid ethyl ester and sn-2 docosahexaenyl monoacylglyceride on plasma and erythrocyte fatty acids in rats.
Ann Nutr Metab 2005; 49(1):49-53

2005 Morgado N, Rigotti A, Valenzuela A.
Comparative effect of fish oil feeding and other fietary fatty acids on plasma lipoproteins, biliary lipids, and hepatic expression of proteins involved in reverse cholesterol transport in the rat.
Ann Nutr Metab 2005; 49(6):397-406

2004 Valenzuela A, von Bernhardi R, Valenzuela V, Ramirez G, Alarcon R, Sanhueza J, Nieto S.
Supplementation of female rats with a-linoleic acid or docosahexaenoic acid leads to the same omega-6/omega-3 LC-PUFA accretion in mother tissues and in fetal and newborn brains.
Ann Nutr Metab 2004; 48:28-35

2004 Valenzuela A, Sanhueza J, Alonso P, Corbari A, Nieto S.
Inhibitory action of conventional food-grade natural antioxidants and of natural antioxidants of new development on the thermal-induced oxidation of cholesterol.
Int J Food Sci Nutr 2004; 55(2):155-162

2004 Valenzuela A, Sanhueza J, Nieto S.
Cholesterol oxidized products in foods: potential health hazards and the role of antioxidants in prevention.
Grasas & Aceites 2004; 55:313-321

2003 Morgado N, Sanhueza J, Nieto S, Valenzuela A.
Effect of the degree of hydrogenation of fish oil on the anzymatic activity and on the fatty acid composition of hepatic microsomes from young and aged rats.
Ann Nutr Metab 2003; 47(3-4):124-131

2002 Valenzuela A, Sanhueza J, Nieto S.
Differential inhibitory effect of alpha-, beta-, gamma-, and delta- tocopherols on the metal- induced oxidation of cholesterol in unilamellar phospholipid-cholesterol liposomes.
J Food Sci 2002; 67(6):2051-2055

2002 Valenzuela A, Sanhueza J, Nieto S.
Effect of synthetic antioxidants on cholesterol stability during the thermal-induced oxidation of a polyunsaturated vegetable oil.
JAOCS 2002; 79(4):325-328

2002 Valenzuela A.
Natural antioxidants: from safety to health benefits.
Biotechnol Feed Ind 2002; 18:323-332

2000 Valenzuela A, Sanhueza J, Nieto S.
Acidos grasos omega-3 de cadena larga en la salud y nutrición humana y animal: un modelo para el desarrollo de alimentos funcionales (Long-chain omega-3 fatty acids in human and animal health and nutrition: a model for development of functional foods).
Aceites y Grasas 2000; 10(4):526-533

2000 Sanhueza J, Nieto S, Valenzuela A.
Thermal stability of some synthetic antioxidants.
JAOCS 2000; 77:933-936

2000 Valenzuela A, Sanhueza J, Nieto S.
Rancidez oxidativa en la industria de nutrición animal: el uso racional de los antioxidantes (Oxidative rancidity in the industrial animal nutrition: the national use of antioxidants).
Aceites y Grasas 2000; 10(2):201-216

2000 Uauy R, Valenzuela A.
Marine oils: the health benefits of n-3 fatty acids.
Nutrition 2000; 16:680-684

1999 Valenzuela A, Sanhueza J, Nieto S.
Sustitutos de grasas ¿Lípidos del futuro? (Fat substitutes: lipids of the future).
Aceites y Grasas 1999; 10:435-442

1999 Morgado N, Sanhueza J, Galleguillos A, Garrido A, Nieto S, Valenzuela A.
Effect of dietary hydrogenated fish oil on the plasma lipoprotein profile and on the fatty acid composition of different tissues of the rat.
Ann Nutr Metab 1999; 43:310-318

1999 Valenzuela A, Garrido A.
Colesterol “Bueno” y Colesterol “Malo”, ¿cuál es el mito y cuál es la realidad? (Good and bad cholesterol. What is myth and what is reality?).
Aceites y Grasas 1999; 9:93-102

1999 Uauy R, Mena P, Valenzuela A.
Essential fatty acids as determinants of lipid requirements in infants, children and adults.
Eur J Clin Nutr 1999; 53(Suppl 1):S66- S77

1999 Valenzuela A, Nieto S, Garrido A.
Acidos grasos poliinsaturados de cadena larga n-3: cuándo y por qué es necesaria la suplementación con estos ácidos grasos (Long chain polyunsaturated fatty acids: when and why is necessary the supplementation with these fatty acids).
Aceites y Grasas 1999; 9:294-299

1999 Nieto S, Gutierrez J, Sanhueza J, Valenzuela A.
Preparation of sn-2 long-chain polyunsaturated monoacylglycerols from fish oil by hydrolysis with a stereo-specific lipase from mucor miehei.
Grasas y Aceites 1999; 50:111-113

1999 Valenzuela A.
El ácido docosahexaenoico (DHA): ¿es realmente un ácido graso esencial? (Docosahexaenoic acid: is really an essential fatty acid?.
Aceites y Grasas 1999; 9(37):571-579

1999 Valenzuela A, Uauy R.
Consumption pattern of dietary fats in Chile: n-6 and n-3 fatty acids.
Int J Food Sci Nutr 1999; 50:127-133

1999 Nieto S, Sanhueza J, Valenzuela A.
Synthesis of structured triacylglycerols containing medium-chain fatty acids by interesterification with a stereoespecific lipase from Mucor miehei.
Grasas y Aceites 1999; 50:199-202

1998 Morgado N, Galleguillos A, Sanhueza J, Garrido A, Nieto S, Valenzuela A.
Effect of the degree of hydrogenation of dietary fish oil on the trans fatty acid content and enzymatic activity of rat hepatic microsomes.
Lipids 1998; 33(7):669-673

1998 Mendez E, Sanhueza J, Nieto S, Speisky H, Valenzuela A.
Fatty acid composition, extraction, fractionation, and stabilization of bullfrog (rana catesbeiana) oil.
JAOCS 1998; 75:67-71

1998 Valenzuela A, Sanhueza J, Nieto S.
Oxidos del colesterol (oxisteroles) en alimentos: factores que condicionan su formación y sus efectos biológicos (Cholesterol oxides in foods: factors conditioning its formation and biological effects).
Aceites y Grasas 1998; 9:271-278

1998 Ganga A, Nieto S, Sanhueza J, Romo C, Speisky H, Valenzuela A.
Concentration and stabilization of n-3 polyunsaturated fatty acids from sardine oil.
JAOCS 1998; 75:733-736

1997 Mendez E, Sanhueza J, Speisky H, Valenzuela A.
Comparison of rancimat evaluation modes to assess oxidative stability of fish oils.
J Am Oil Chem Soc 1997; 74(3):331-332

1997 Mendez E, Sanhueza J, Speisky H, Valenzuela A.
Comparison of two Rancimat evaluation modes in the assessment of the relative stability of fish oil.
J Am Oil Chem Soc 1997; 74:331-332

1997 Valenzuela A, Sanhueza J, Nieto S.
Digestión, absorción y transporte de los ácidos grasos: una perspectiva diferente en la interpretación de sus efectos nutricionales (Digestion, absorption and transport of fatty acids: a different perspective on the interpretation of their nutritional effects).
Aceites y Grasas 1997; 10:582-588

1997 Rodriguez R, Sanhueza J, Valenzuela A, Nieto S.
Hidrólisis del aceite de coco (Cocos nucífera L.) mediante enzimas estereoespecíficas y sin especificidad posicional (Coconut oil hydrolysis by esteroespecific enzymes with no positional specialty).
Grasas y Aceites 1997; 48:6-10

1997 Nieto S, Cordoba AM, Sanhueza J, Valenzuela A.
Obtention of highly purified fractions of eicosapentaenoic acid and docosahexaenoic acid from sardine oil by silver-resin chromatography: a semi-preparative procedure.
Grasas y Aceites 1997; 48:197-199

1997 Valenzuela A.
Efectos biológicos y nutricionales de los ácidos grasos trans ¿Cuánto es mito y cuánto es realidad? (Biological and nutritional effects of trans fatty acids: myths and reality).
Grasas y Aceites 1997; 48:263-270

1996 Uauy R, Valenzuela A.
Marine oils: the health benefits of n-3 fatty acids.
Nutr Rev 1996; 54(11 pt 2):S102-S108

1996 Valenzuela A, Nieto S.
Synthetic and natural antioxidants: food quality protectors.
Grasas y Aceites 1996; 47(3):186-196

1996 Mendez E, Sanhueza J, Speisky H, Valenzuela A.
Validation of the Rancimat test for the assessment of the relative stability of fish oils.
J Am Oil Chem Soc 1996; 73:1033-1037

1996 Bannach R, Valenzuela A, Cassels BK, Nuñez-Vergara L, Speisky H.
Cytoprotective and antioxidant effects of boldine on tert-butyl hydroperoxide-induced damage to isolated hepatocytes.
Cell Biol Toxicol 1996; 12:89-100

1995 Valenzuela A, King J, Nieto S.
Trans fatty acid isomers from hydrogenated fats: the controversy about health implications.
Grasas y Aceites 1995; 46(6):369-375

1995 Valenzuela A, Nieto S.
Natural antioxidants: a new perspective for the problem of oxidative rancidity of lipids.
Biotecnol Feed Ind 1995; 11:207-220

1995 Valenzuela A, Nieto S.
Los antioxidantes: protectores de la calidad en la industria alimentaria (Antioxidants: quality protectors for the food industry).
Aceites y Grasas 1995; 5:310-321

1995 Garrido A, Valenzuela A.
Dietary polyunsaturated fatty acids, and tissue oxidative stress: the effect of d, 1-alpha-tocopherol.
Ciencia e Cultura 1995; 47(5/6):363-368

1994 Valenzuela A, Nieto S.
Biotechnology of lipids: the use of lipases for the structural modification of fats and oils.
Grasas y Aceites 1994; 45(5):50-62

1994 Valenzuela A, Nieto S.
Innovación tecnológica aplicable a los aceites marinos ricos en ácidos grasos N-3 para permitir su uso nutricional y farmacológico: un desafío para la presente década (Technological innovation applicable to marine oils rich in N-3 fatty acids to allow its nutritional and pharmacological use: a challenge for the current decade).
Arch Latinoam Nutr 1994; 44(4):223-231

1994 Gonzalez-Cabello R, Speisky H, Bannach R, Valenzuela A, Feher J, Gergely P.
Effects of boldine on cellular immune functions in vitro.
J Invest Allergol Clin Immunol 1994; 4(3):139-145

1994 Backhouse N, Del Porte C, Givemau M, Cassels BK, Valenzuela A, Speisky H.
Anti-inflammatory and anti-pyretic effects of boldine.
Agents Actions 1994; 42:114-117

1993 Nieto S, Galleguillos A, Sanhueza J, Valenzuela A.
Desodorización de aceite de pescado mediante destilación a alto vacío: preservación de las características químicas del aceite (Deodorization of fish oil by high vacuum distillation: preservation of the chemical characteristics of the oil).
Grasas y Aceites 1993; 44(1):35-38

1993 Valenzuela A, Nieto S, Uauy R.
Technological challenges to evaluate n-3 polyunsaturated fatty acids from marine oils for nutritional and pharmacological uses.
Grasas y Aceites 1993; 44(1):39-46

1993 Speisky H, Valenzuela A, Nieto S, Cassels B, Nuñez-Vergara L.
Determination of boldine in plasma by high performance liquid chromatography.
J Chromatogr 1993; 612(2):315-319

1993 Asencio M, Cassels B, Speisky H, Valenzuela A.
(R)-and (S)-Coclaurine from the bark of Peumos boldus.
Fitoterapia 1993; 64(5):455-458

1993 Garrido A, Garate M, Valenzuela A.
Changes in the antioxidant capacity of blood plasma are pro
duced after ingestion of high doses of fish oil. Res Commun Chem Pathol Pharmacol 1993; 82(3):367-370

1993 Nieto S, Garrido A, Sanhueza J, Loyola LA, Morales G, Leighton F, Valenzuela A.
Flavonoids as stabilizers of fish oil: an alternative to synthetic antioxidants.
JAOCS 1993; 70(8):773-778

1993 Garrido A, Garate M, Campos R, Nieto S, Villa A, Valenzuela A.
Increased susceptibility of cellular membranes to the induction of oxidative stress after ingestion of high doses of fish oil: effect of aging and protective action of dl-alpha tocopherol supplementation.
J Nutr Biochem 1993; 4:118-122

1993 Valenzuela A, Nieto S, Uauy R.
Desafíos tecnológicos para evaluar ácidos grasos N-3 poliinsaturados en aceites marinos de uso alimenticio y farmacológico (Technological challenges to evaluate marine n-3 poly-unsaturated fatty acids for food and pharmacologic uses).
Aceites y Grasas 1993; 2(2):53-62

1992 Uauy R, Valenzuela A.
Marine oils as a source of omega-3 fatty acids in the diet: how to optimize the health benefits.
Progr Food Nutr Sci 1992; 16:199-243

1992 Sanhueza J, Valdes J, Campos R, Garrido A, Valenzuela A.
Changes in the xanthine-dehydrogenase<7xanthine oxidase ratio in the rat kidney subjected to ischemia-reperfusion stress: preventive effect of some flavonoids.
Res Commun Chem Pathol Pharmacol 1992; 78:211-218

1992 Villa A, Carrasco G, Valenzuela A, Garrido A.
The effect of calcium on disodium monofluorophosphate absorption from the gastrointestinal tract of rats.
Res Commun Chem Pathol Pharmacol 1992; 77(3)367-374

1991 Valenzuela A, Nieto S, Cassels B, Speisky H.
Inhibitory effect of boldine on fish oil oxidation.
J Am Oil Chem Soc 1991; 68(12):935-937

1991 Garrido A, Arancibia C, Campos R, Valenzuela A.
Acetaminophen does not induce oxidative stress in isolated rat hepatocytes: its probable antioxidant effect is potentiated by the flavonoid silybin.
Pharmacol Toxicol 1991; 69:9-12

1991 Cañas P, Valenzuela A.
Rol biológico y nutricional de la taurina y sus derivados en la fisiología orgánica y celular (Biological and nutritional role of taurine and its derivatives on cellular and organic physiology).
Arch Latinoam Nutr 1991; 41(2):139-151

1991 Valenzuela A.
The biological significance of malondialdehyde determination in the assessment of tissue oxidative stress.
Life Sci 1991; 48:301-309

1990 Campos R, Garrido A, Guerra R, Valenzuela A.
Increased resistance against oxidative stress is observed during a short period of renal reperfusion after a temporal ischaemia.
Free Rad Res Commun 1990; 10(4-5):259-264

1990 Dinamarca E, Garrido F, Valenzuela A.
Simple high vacuum distillation equipment for deodorizing fish oil for human consumption.
Lipids 1990; 25(3):170-171

1990 Thielemann L, Oberhauser E, Rosenblut G, Videla L, Valenzuela A.
Sulfur containing amino acids that increase renal glutathione protect the kidney against papillary necrosis induced by 2-bromoethylamine.
Cell Biochem Funct 1990; 8:19-24

1989 Campos R, Garrido A, Guerra R, Valenzuela A.
Silybin dihemisuccinate protects against glutathione depletion and lipid peroxidation induced by acetaminophen on rat liver.
Planta Medica 1989; 55(5):417-419

1989 Garrido a, Fairlie J, Campos R, Guerra R, Valenzuela A.
The flavonoid silybin ameliorates the protective effect of ethanol on acetaminophen hepatotoxicity.
Res Commun Subst Abuse 1989; 10(3):193-196

1989 Garrido A, Garrido F, Guerra R, Valenzuela A.
Ingestion of high doses of fish oil increases the susceptibility of cellular membranes to the induction of oxidative stress.
Lipids 1989; 24:833-835

1989 Cañas P, Guerra R, Valenzuela A.
Antioxidant properties of hypotaurine: comparison with taurine, glutathione and B-alanine.
Nutr Rep Int 1989; 39(2):433-438

1989 Valenzuela A, Aspillaga M, Vial S, Guerra R.
Selectivity of silymarin on the increase of glutathione content in different tissues of the rat.
Planta Medica 1989; 55(5):420-424

1989 Valenzuela A, Bustamante JC, Videla C, Guerra R.
Effect of silybin dihemisuccinate on the ethanol metabolizing systems of the rat liver.
Cell Biochem Funct 1989; 7:173-178

1988 Garrido A, Guerra R, Valenzuela A.
The flavonoid silymarin increases the permeability of rat bone marrow cells to (3H)-uridine.
Res Commun Chem Pathol Pharmacol 1988; 61(2):273-276

1988 Donoso M, Valenzuela a, Silva E.
Tryptophan-riboflavin photo-induced adduct and hepatic dysfunction in rats.
Nutr Rep Int 1988; 37:599-606

1988 Salim-Hanna M, Valenzuela A, Silva E.
Riboflavin status and photo-induced riboflavin binding to the proteins of the rat ocular lens.
Int J Vit Nutr Res 1988; 58(1):61-66

1987 Valenzuela A, Guerra R, Garrido A.
Silybin dihemisuccinate protects rat erythrocytes against phenylhydrazine-induced lipid peroxidation and hemolysis.
Planta Medica 1987; 53(5):402-405

1987 Videla L, Fernandez V, Valenzuela A.
Age dependent changes in rat liver lipid peroxidation and glutathione content induced by acute ethanol ingestion.
Cell Biochem Funct 1987; 5:273-280

1986 Valenzuela A, Guerra R.
Differential effect of silybin on the Fe2+ -ADP and t-butyl hydroperoxide-induced microsomal lipid peroxidation.
Experientia 1986; 42:139-141

1986 Valenzuela A, Guerra R, Lazcano L, Cañas P.
Differential prooxidative effect of adult and fetal hemoglobin.
FEBS Lett 1986; 196:353-356

1986 Valenzuela A, Guerra R, Videla L.
Antioxidant properties of the flavonoids silybin and (+)-cyanidanol-3: comparison with butylated hydroxyanisole and butylated hydroxytoluene.
Planta Medica 1986; Nº6:438-440

1985 Uauy R, Castillo Duran C, Fisberg M, Fernandez N, Valenzuela A.
Red cell superoxide dismutase activity in nutritional copper deficiency.
J Nutr 1985; 115:1650-1655

1985 Valenzuela A, Barria T, Guerra R, Garrido A.
Inhibitory effect of the flavonoid silymarin on erythrocyte hemolysis induced by phenylhydrazine.
Biochem Biophys Res Commun 1985; 126(2):712-718

1985 Fernandez V, Barrientos X, Kipreos K, Valenzuela A, Videla L.
Superoxide radical generation, NADPH oxidase activity, and cytochrome P-450 content of rat liver microsomal fractions in an experimental hyperthyroid state. Relation to lipid peroxidation.
Endocrinology 1985; 117(2):496-501

1985 Valenzuela A, Guerra R.
Protective effect of the flavonoid silybin dihemisuccinate on the toxicity of phenylnydrazine on rat liver.
FEBS Lett 1985; 181(2):291-294

1985 Valenzuela A, Lagos C, Schmidt K, Videla L.
Silymarin protection against hepatic lipid peroxidation induced by acute ethanol intoxication in the rat.
Biochem Pharmacol 1985; 34(12):2209-2212

1985 Videla L, Fernandez V, Valenzuela A.
Effect of ethanol and iron on the hepatic and biliary levels of glutathione and lipid peroxidative indexes.
Alcohol 1985; 2(3):457-462

1985 Videla L, Valenzuela A, Fernandez V, Kriz A.
Differential lipid peroxidative response of rat liver and lung tissues to glutathione depletion induced in vivo by diethyl maleate: effect of the antioxidant flavonoid (+) -cyanidanol-3.
Biochem Int 1985; 10(3):425-433

1983 Castillo Duran C, Fisberg M, Valenzuela A, Egaña JI, Uauy R.
Controlled trial of copper supplementation during the recovery from marasmus.
Am J Clin Nutr 1983; 37:898-903

1973 Minguell J, Sierralta W, Valenzuela A, Romero C, Valladares L, Perretta M.
Molecular mechanisms of the erythropoietic process.
Acta Physiol Latinoam 1973; 23:541-543

Revistas Nacionales

2012 Sanhueza J, Valenzuela A. Nutrigenómica: Revelando los aspectos moleculares de una nutrición personalizada (Nutrigenomics: Revealing molecular aspects of a personalized nutrition). Rev Chil Nutr 2012; 39(1):71-85

2011 Valenzuela A, Yáñez CG, Golusda C. El ostión del Norte Chileno (Argopecten purpuratus), un alimento de alto valor nutricional (The scallop from the Chilean North (Argopecten Purpuratus) , a food with a high nutricional value). Rev Chil Nutr 2011; 38:148-155

2011 Valenzuela R, Tapia G, Gonzáles M, Valenzuela A. Acidos grasos omega-3 (EPA y DHA) y su aplicación en diversas situaciones clínicas (Omega-3 fatty acids (EPA and DHA) and its application in diverse clinical situations). Rev Chil Nutr 2011: 38(3):356-367

2011 Valenzuela R, Bascuñán K, Chamorro R, Valenzuela A. Acidos grasos omega-3 y cáncer, una alternativa nutricional para su prevención y tratamiento (Omega-3 fatty acids and cancer, a nutritional alternative for its prevention and treatment). Rev Chil Nutr 2011; 38(2):219-226

2011 Valenzuela A. ¿Por qué comemos lo que comemos? (Why we eat what we eat?). Rev Chil Nutr 2011; 38(2):198-209

2010 Valenzuela A, Yáñez CG, Golusda C. ¿Mantequilla o margarina? Diez años después ((Butter or margarine? ten years after). Rev Chil Nutr 2010; 37:505-513

2010 Durán R, Valenzuela A. La experiencia japonesa con los alimentos Foshu ¿los verdaderos alimentos funcionales? (The japanese experience with Foshu foods the true functional foods?). Rev Chil Nutr 2010; 37(2):224-233

2010 Valenzuela A. El café y sus efectos en la salud cardiovascular y en la salud materna (Coffee, caffeine, and its effects on cardiovascular health and maternal health). Rev Chil Nutr 2010; 37(4):514-523

2009 Valenzuela A, Sanhueza J.
Aceites de origen marino: su importancia en la nutrición y en la ciencia de alimentos (Marine oils: nutritional and food science relevance).
Rev Chil Nutr 2009; 36(3):246-257

2009 Obregón AM, Valenzuela A.
Acido linoleico conjugado (ALC), metabolismo de lípidos y enfermedad cardiovascular (Conjugated linoleic acid (ALC), lipid metabolism and cardiovascular disease).
Rev Chil Nutr 2009; 36(3):258-268

2009 Valenzuela R, Bascuñán K, Valenzuela A, Chamorro R. Acidos grasos omega-3, enfermedades psiquiátricas y neurodegenerativas: Un nuevo enfoque preventivo y terapéutico (Omega-3 fatty acids, neurodegenerative and psychiatric diseases: A new preventive and therapeutic approach). Rev Chil Nutr 2009; 36(4):1120-1128

2008 Valenzuela A, Sanhueza J.
Estructuración de lípidos y sustitutos de grasas, ¿Lípidos del futuro? (Structured lipids and fat substitutes, the future lipids?).
Rev Chil Nutr 2008; 35(4):394-405

2008 Valenzuela A.
Acidos grasos con isomería trans I. Su origen y los efectos en la salud humana (Isomeric trans fatty acids I. Origin and effects in human health).
Rev Chil Nutr 2008; 35(3):162-171

2008 Valenzuela A.
Acidos grasos con isomería trans II. Situación de consumo en Latinoamérica y alternativas para su sustitución (Isomeric trans fatty acids II. Consumption trans fatty acids II. Consumption in Latin America and alternatives for substitution).
Rev Chil Nutr 2008; 35(3):172-180

2008 Valenzuela R, Bascuñán K, Valenzuela A.
Acido docosahexaenoico (DHA): Una perspectiva nutricional para la prevención de la enfermedad de Alzheimer (Docosahexaenoic acid (DHA): A nutritional view for the prevention of Alzheimer's disease).
Rev Chil Nutr 2008; 35(Supl 1):250-261

2007 Valenzuela A.
El chocolate, un placer saludable (Chocolate, a healthy pleasure).
Rev Chil Nutr 2007; 34(3):180-190

2007 Valenzuela A.
Evolución bioquímica de la nutrición: Del mono desnudo al mono obeso ((Biochemical evolution of nutrition: From the naced ape to the obese ape).
Rev Chil Nutr 2007; 34(4):282-290

2006 Valenzuela A, Morgado N.
Breve historia de la relación entre el colesterol y las enfermedades cardiovasculares (Brief history of the relationship between cholesterol and cardiovascular diseases).
Rev Chil Nutr 2006; 33(2):130-134

2006 Sanhueza J, Valenzuela A.
Receptores nucleares y regulación de la expresión génica por ácidos grasos poliinsaturados: algo más que producción de energía y esencialidad (Nuclear recptors and regulation of gene expression of polyunsaturated fatty acids: something more than energy production and essentiality).
Rev Chil Nutr 2006; 33(2):150-161

2005 Valenzuela A, Morgado N.
Las grasas y aceites en la nutrición humana: algo de su historia (Fats and oils in human nutrition: an historical overview).
Rev Chil Nutr 2005; 32(2):88-94

2005 Valenzuela A.
El salmón: un banquete de salud (Salmon: a health banquet).
Rev Chil Nutr 2005; 32(1):8-17

2005 Valenzuela A, Nieto S, Golusda C, Muñoz P, Corvari A.
Composición de materias grasas y relación de ácidos grasos omega-6/omega-3 de cecinas de consumo habitual en la Región Metropolitana de Chile: una reevaluación el año 2004 ((Fat composition and omega-6/omega-3 fatty acid ratio of the most frequently consumed sausages in the Metropolitan Region of Chile: a reevaluation in the year 2004).
Rev Chil Nutr 2005; 32(1):37-41

2004 Valenzuela A.
El consumo de té y la salud: características y propiedades benéficas de esta bebida milenaria (Tea consumption and health: beneficial characteristics and properties of this ancient beverage).
Rev Chil Nutr 2004; 31(2):72-82

2004 Sanhueza J, Nieto S, Valenzuela A.
Acido docosahexanoico (DHA), desarrollo cerebral, memoria y aprendizaje: la importancia de la suplementación perinatal (Docosahexaenoic acid (DHA), brain development, memory and learning: the importance of perinatal supplementation).
Rev Chil Nutr 2004; 31(2):84-92

2004 Valenzuela A, Ronco AM.
Fitoesteroles y fitoestanoles: aliados naturales para la protección de la salud cardiovascular (Phytosterols and phytostanols: natural allied for the protection of cardiovascular health).
Rev Chil Nutr 2004; 31(Supl 1):161-169

2004 Valenzuela A, Sanhueza J, Nieto S.
¿Cuál es el mejor aceite? (Which is the best oil?).
Prinal en línea 2004; 5(17):4-10

2003 Valenzuela A, Nieto S.
Acidos grasos omega-6 y omega-3 en la nutrición perinatal: su importancia en el desarrollo del sistema nervioso y visual (Omega-6 and omega-3 fatty acids in perinatal nutrition: their importance in the development of the nervous and visual systems).
Rev Chil Pediatr 2003; 74(2):149-157

2003 Valenzuela A, Sanhueza J, Nieto S.
Cholesterol oxidation: health hazard and the role of antioxidants in prevention.
Biol Res 2003; 36(3-4):291-302

2002 Sanhueza J, Nieto S, Valenzuela A.
Acido linoleico conjugado: un ácido graso con isomería trans potencialmente beneficioso (Conjugated linoleic acid: a trans isomer fatty acid potentially beneficial).
Rev Chil Nutr 2002; 29(2):98-105

2002 Valenzuela A, Sanhueza J, Nieto S.
¿Es posible mejorar la calidad nutricional de los aceites comestibles? (Is it possible to improve the nutritional quality of edible oils?).
Rev Chil Nutr 2002; 29(Supl 1):174-180

2002 Valenzuela A, Sanhueza J, Nieto S.
Oxidos del colesterol (oxisteroles): factores que condicionan su formación, efectos biológicos y su presencia en los alimentos (Cholesterol oxides (oxisterols): factors conditioning their formation, biological effects and content in foods).
Rev Chil Nutr 2002; 29(2):116-124

2002 Valenzuela A, Sanhueza J, Nieto S.
El uso de lípidos estructurados en la nutrición: una tecnología que abre nuevas perspectivas en el desarrollo de productos innovadores (Structured lipids in nutrition: a technology for the development of novelty products).
Rev Chil Nutr 2002; 29(2):106-114

2001 Valenzuela A, Nieto S, Aparicio M, Guzman E.
Composición de materias grasas de cecinas de consumo habitual en la Región Metropolitana de Chile (Fat composition of the most frequently consumed sausages in Region Metropolitana of Chile).
Rev Chil Nutr 2001; 28(1):183-187

2001 Valenzuela A, Sanhueza J, Nieto S.
Digestión, absorción y transporte de las grasas: ¿Cuánto es utilizable desde el punto de vista nutricional? (Digestion, absorption, and transport of fats: how nutritionally available are?).
Rev Chil Nutr 2001; 28(3):396-405

2001 Valenzuela A, Nieto S.
El ácido docosahexaenoico (DHA) en el desarrollo fetal y en la nutrición materno-infantil (Docohexaenoic acid (DHA) in fetal development and infant nutrition).
Rev Med Chil 2001; 129:1203-1211

2000 Valenzuela A.
Estrés oxidativo, una enfermedad de nuestro tiempo: el beneficio de la suplementación de la dieta con sustancias antioxidantes (Oxidative stress, an illness at present: the benefit of the diet supplement with antioxidant substances).
Reumatología 2000;16(2):57-66

2000 Valenzuela A, Sanhueza J, Nieto S.
Acidos grasos omega-3 de cadena larga en la nutrición humana y animal: un modelo de alimentos funcionales (Long- chain omega-3 fatty acids in human and animal nutrition: a model for functional foods).
Rev Chil Nutr 2000; 27:345-351

2000 Valenzuela A, Garrido A.
Los fitosteroles: agentes hipocolesterolémicos naturales de índole no farmacológico (Phytosterols: hypocholesterolemic agents of non-pharmacological origin).
Rev Chil Nutr 2000; 27:220-225

1999 Valenzuela A, Morgado N.
Trans fatty acid isomers in human health and in the food industry.
Biol Res 1999; 32(4):273-287

1999 Valenzuela A, Morgado N.
Trans fatty acid isomers in human health and in food industry.
Biol Res 1999; 32:273-287

1999 Valenzuela A, Uauy R.
Mantequilla o margarina, ¿Cuál es mejor para consumir?: implicancias para la nutrición y salud humana (Butter or margarine, which is better to consume?: implications for nutrition and human health).
Rev Chil Nutr 1999; 26(1):70-79

1999 Valenzuela A.
El ácido docosahexaenoico(DHA): su esencialidad y requerimientos (Docosahexaenoic acid (DHA): essentiality and requirements).
Rev Chil Nutr 1999; 26:279-287

1998 Valenzuela A, Garrido A.
Importancia nutricional de los ácidos grasos poliinsaturados n-3 de cadena larga: el beneficio de su suplementación (Nutritional importance of n-3 long-chain polyunsaturated fatty acid: the benefits of supplementation).
Rev Chil Nutr 1998; 25:21-29

1995 Valenzuela A, Romo C, Nieto S.
Tecnologías aplicables a la industrialización de los aceites marinos para permitir su aplicación en la alimentación(Applicable technologies to marine oil industry to allow its application in the food industry).
Alimentos 1995; 20:1-14

1994 Valenzuela A, Nieto S.
Lípidos para el futuro. II: sustitutos hipocalóricos o no calóricos de los lípidos (Lipids of the future. II. Hypocaloric or non caloric lipids substitutes).
Alimentos 1994; 19(5-6):58-64

1994 Valenzuela A, Sanhueza J, Nieto S.
Lípidos para el futuro: el uso de la biotecnología para la formulación de nuevos tipos de lípidos (Lipids for the future: the use of biotechnology for the development of new kind of lipids).
Alimentos 1994; 19(4):45-50

1994 Valenzuela A, Garrido A.
Biochemical basis of the pharmacological action of the flavonoid silymarin and of its structural isomer silibinin.
Biol Res 1994; 27:105-112

1994 Olivares M, Hertrampf E, Wegner D, Capurro MT, Letelier A, Valenzuela A.
Valores normales del hemograma y otras variables hematológicas en sujetos mayores de 60 años (Normal blood cell counts in people 60 years of age and older).
Rev Med Chil 1994; 122:1289-1293

1994 Valenzuela A, Perreta M.
Envejecimiento celular, la hipótesis oxidativa: un punto de vista bioquímico (Cellular aging, the oxidative hypothesis: a biochemical approach).
Geriatrika 1994; 3(7):131-139

1990 Valenzuela A.
Activación metabólica: un mecanismo biológico que aumenta la toxicidad de los xenobióticos (Metabolic activation may increase toxicity from foreign substances).
Rev Med Chil 1990; 118(9):1028-1034

1989 Cañas P, Valenzuela A.
Rol biológico y fisiológico de la taurina y sus derivados (Physiologic role of taurine and its derivatives).
Rev Med Chil 1989; 117:454-459

1989 Valenzuela A, Videla L.
Formas activas del oxígeno, stress oxidativo y su proyección patológica (Active forms of oxygen: pathologic significance oxidative stress).
Rev Med Chil 1989; 117(1):60-67

1988 Valenzuela A, Campos R, Garrido A.
Estudios sobre el mecanismo bioquímico de acción del flavonoide silybina: relación con sus propiedades terapéuticas (Studies on the biochemical mechanism of action of the flavonoid silybin: relationship with its therapeutic properties).
Arch Biol Med Exp 1988; 27:75-83

1988 Cañas P, Olivares M, Celedon C, Llaguno S, Valenzuela A.
Actividad del sistema de defensa antioxidante y agresión oxidativa en eritrocitos de recién nacidos de bajo peso y distintas edades gestacionales (Antioxidant enzyme defense system in cord blood from infants).
Rev Chil Pediatr 1988; 59:83-88

1988 Valenzuela A, Guerra R.
Perspectivas tecnológicas en el desarrollo de nuevos tipos de antioxidantes: uso de liposomas que contienen las enzimas superóxido dismutasa y catalasa en la inhibición de peroxidación de la grasa láctea (Technological perspectives of new types of antioxidants use of liposomes containing superoxide dismutase and catalase in inhibition of peroxidation of milk fat).
Alimentos 1988; 13(2):35-40

1982 Valenzuela A.
Vitamina E: La vitamina E en búsqueda de una enfermedad.
Rev Chil Nutr 1982; 10(3):199-211

1976 Perretta M, Valladares L, Romero C, Sierralta W, Valenzuela A, Spencer E, Cañas P, Minguell JJ.
Hormone action on the cell nucleus: Effect of erythropoietin testosterone on bone marrow.
Arch Biol Med Exp 1976; 10:35-40

1970 Perretta M, Valladares L, Romero C, Sierralta W, Valenzuela A, Spencer E, Cañas P, Minguell J.
Hormone action on the cell nucleus: effect of erythropoietin and testosterone on bone marrow.
Arch Biol Med Exp 1970; 10:35-40

Valenzuela R, Bascuñán K, Chamorro R, Valenzuela A. Acidos grasos omega-3 y cáncer, una alternativa nutricional para su prevención y tratamiento (Omega-3 fatty acids and cancer, a nutritional alternative for its prevention and treatment). Rev Chil Nutr 2011; 38(2):219-226

Publicaciones

Libros

1988 Monckeberg F, Agosin E, Perretta M, Rosemblatt M, Spencer E, Valenzuela A, Valladares L.
La revolución de la bioingeniería (The revolution of bioengineering).
Santiago: Publicaciones Técnicas Mediterráneo; 1988

1983 Yañez E, Valenzuela A, Oliva P., editores.
Las proteínas en la nutrición y en la industria.
Chillán: Instituto Profesional de Chillán; Universidad de Chile, INTA; 1983

Capítulos de Libros

2005 Valenzuela A, Uauy R.
Funciones biológicas y metabolismo de los ácidos grasos esenciales y de sus derivados activos.
En: Gil A., editor. Tratado de nutrición. Madrid: Acción Médica; 2005. v.1, p.429-450

2001 Valenzuela A.
Acidos graxos omega-6 e omega-3 na nutricao e saude humana.
En: De Angelis R., editor. Importancia de alimentos vegetais na protecao da saude. Sao Paulo: Atheneu; 2001. p.235-244

2000 Valenzuela A, Sanhueza J, Nieto S.
Sustitutos de grasas ¿lípidos del futuro? (Fat substitutes. Lipids of the future?).
En: Albala C, Kain J, Burrows R, Diaz E., editores. Obesidad: un desafío pendiente. Santiago: Editorial Universitaria; 2000. p.187-197

1997 Uauy R, Valenzuela A.
Use de preferencia aceites vegetales y disminuya las grasas de origen animal (Use preferally vegetal oils and lower fats from animal source).
En: Castillo C, Uauy R, Atalah E., editores. Guías de alimentación para la población chilena. Santiago: Ministerio de Salud / Universidad de Chile, INTA; 1997. p.91-99

1994 Valenzuela A.
Boldine as a natural antioxidant.
In: Turner D., editor. Biotechnology in Chile to day: an entrepreneurial perspective. Santiago: Eurochile-INUAL; 1994. p.68

1993 Valenzuela A, Nieto S, Uauy R.
Improvement of fish oil technology to allow human consumption.
In: Valiente S, Avila B, Valiente G, Valenzuela S, Robledo A., editors. Food and nutrition policies and programs in Chile: a successful experience. Santiago: University of Chile, INTA, Group of Food and Nutrition Policies and Programs; 1993. p.461-472

1988 Campos R, Garrido A, Guerra R, Valenzuela A.
Acetaminophen hepatotoxicity in rats is attenuated by silybin dihemisuccinate.
In: Plant flavonoids in biology and medicine. II: Biochemical, cellular and medicinal properties. New York: Alan R. Liss, Inc. ; 1988. p.375-378

Informes Internacionales

Informes Nacionales

2009 Obregón AM, Valenzuela A.
Acido linoleico conjugado (ALC), metabolismo de lípidos y enfermedad cardiovascular (Conjugated linoleic acid (ALC), lipid metabolism and cardiovascular disease).
Rev Chil Nutr 2009; 36(3):258-268

Monografías

Programas Informáticos