Latorre Mora Mauricio Alejandro

Profesor Adjunto
Unidad Académica: 
Email: 
mlatorre@inta.uchile.cl
Teléfono: 
(56) 229781511
Grado Académico: 
Doctor en Ciencias, mención Biología Molecular, Celular y Neurociencias
Áreas de Interés: 
Metales
Biología de Sistemas
Biotecnología
Reseña: 

Imbalance in metals homeostasis leads to several problems for the human health. From a systemic biology perspective, our research line has been focused in understanding how changes in bioavailability of metals alter the organism. Our laboratory is a pioneer in research of System Biology and Metals. We have published several articles in this field, developing new protocols in  terms of transcriptional regulatory networks construction and metal metabolism analysis.

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Publicaciones

2016 Latorre M, Cortés MP, Travisany D, Di Genova A, Budinich M, Reyes-Jara A, Hödar C, González M, Parada P,Bobadilla-Fazzini RA, Cambiazo V, Maass A. The bioleaching potential of a bacterial consortium. Bioresour Technol 2016 Jul 6; 218:659-666
2016 Del Pozo T, Gutiérrez-Garcia R, Latorre M, González M, Suazo M. Identification of reference genes for quantitative real-time PCR studies in human cell lines under copper and zinc exposure. Biometals. 2016; 29(5):935-944
2016 DebRoy S, Saldaña M, Travisany D, Montano A, Galloway-Peña J, Horstmann N, Yao H, González M, Maass A,Latorre M, Shelburne SA. A multi-serotype approach clarifies the catabolite control protein a regulon in the major human pathogen group a streptococcus. Sci Rep. 2016 Sep 1; 6:32442
2016 Acuña M, Castro-Fernández V, Latorre M, Castro J, Schuchman EH, Guixé V, González M, Zanlungo S. Structural and functional analysis of the ASM p.Ala359Asp mutant that causes acid sphingomyelinase deficiency. Biochem Biophys Res Commun. 2016 Oct 21;479(3):496-501
2016 Bordron P, Latorre M, Cortés MP, González M, Thiele S, Siegel A, Maass A, Eveillard D. Putative bacterial interactions from metagenomic knowledge with an integrative systems ecology approach. Microbiologyopen 2016; 5(1):106-117
2016 Cordero N, Maza F, Navea-Perez H, Aravena A, Marquez-Fontt B, Navarrete P, Figueroa G, González M, Latorre M, Reyes-Jara A. Different tanscriptional responses from slow and fast growth rate strains of Listeria monocytogenes adapted to low temperature. Front Microbiol 2016 Mar 1; 7:229
2015 Latorre M, Low M, Gárate E, Reyes-Jara A, Murray BE, Cambiazo V, González M. Interplay between copper and zinc homeostasis through the transcriptional regulator Zur in Enterococcus faecalis. Metallomics 2015; 7(7):1137-1145
2015 Quiroz N, Rivas N, Del Pozo T, Burkhead J, Suazo M, González M, Latorre M. Transcriptional activation of glutathione pathways and role of glucose homeostasis during copper imbalance. Biometals 2015; 28(2):321-328
2015 Latorre M, Quesille-Villalobos AM, Maza F, Parra A, Reyes-Jara A. Synergistic effect of copper and low temperature over Listeria monocytogenes. Biometals 2015; 28(6):1087-1092
2015 Mandakovic D, Cabrera P, Pulgar R, Maldonado J, Aravena P, Latorre M, Cambiazo V, González M. Complete genome sequence of Microbacterium sp. CGR1, bacterium tolerant to wide abiotic conditions isolated from the Atacama Desert. J Biotechnol 2015; 216:149-150
2014 Latorre M, Galloway-Peña J, Roh JH, Budinich M, Reyes-Jara A, Murray BE, Maass A, González M. Enterococcus faecalis reconfigures its transcriptional regulatory network activation at different copper levels. Metallomics 2014; 6(3):572-581
2014 Travisany D, Cortés MP, Latorre M, Di Genova A, Budinich M, Bobadilla-Fazzini RA, Parada P, González M, Maass A. A new genome of Acidithiobacillus thiooxidans provides insights into adaptation to a bioleaching environment. Res Microbiol 2014 2014; 165(9):743-752
2012 Hödar C, Moreno P, di Genova A, Latorre M, Reyes-Jara A, Maass A, González M, Cambiazo V. Genome wide identification of Acidithiobacillus ferrooxidans (ATCC 23270) transcription factors and comparative analysis of ArsR and MerR metal regulators. Biometals 2012; 25(1):75-93
2012 López G, Latorre M, Reyes-Jara A, Cambiazo V, González M. Transcriptomic response of Enterococcus faecalis to iron excess. Biometals 2012; 25(4):737-747
2011 Latorre M, Olivares F, Reyes-Jara A, López G, González M. CutC is induced late during copper exposure and can modify intracellular copper content in Enterococcus faecalis. Biochem Biophys Res Commun 2011; 406(4):633-637
2010 Reyes-Jara A, Latorre M, López G, Bourgogne A, Murray BE, Cambiazo V, González M. Genome-wide transcriptome analysis of the adaptive response of Enterococcus faecalis to copper exposure. Biometals 2010; 23(6):1105-1112
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